Description
Description
FOXO4-DRI is a senolytic peptide designed to eliminate senescent “zombie” cells by interrupting the FOXO4-p53 interaction, triggering apoptosis in damaged cells without harming healthy ones. It shows promise in reversing age-related physical decline, improving healthspan, reducing inflammation, increasing energy, and reversing chemotherapy-induced damage
- Targeted Elimination of Senescent Cells: It selectively induces apoptosis in senescent (non-functional, inflammatory) cells by inhibiting their ability to evade death via p53.
- Enhanced Physical Function and Healthspan: Research indicates it can improve physical fitness, reduce age-related stiffness, and boost overall vitality.
- Reduced Chronic Inflammation: By clearing senescent cells, it reduces the “zombie cell” load, which decreases inflammatory markers (\(Il-1\beta, Il-6, Tnf-\alpha\)) that contribute to aging.
- Improved Cardiovascular and Tissue Health: Studies show it can increase vascular elasticity, reduce vascular ROS (reactive oxygen species), and potentially improve liver function.
- Reversal of Chemotherapy Side Effects: Research suggests it can counteract the negative effects of senescence caused by chemotherapy, such as, for example, doxorubicin-induced damage.
- Potential Skin Rejuvenation:
Composition
- FOXO4: 10 mg
- Appearance: lyophilized powder in a sealed research vial
Research Focus (non-clinical)
- Investigation of FOXO4-p53 interaction in cellular senescence models
- Studies of apoptosis induction pathways in aging research
- Peptide identity and purity verification via HPLC/LC-MS
- Stability and solubility profiling under various laboratory storage conditions
Documentation
- Lot-specific COA available
- Batch and lot traceability
Important Notice
- For research use only
- Not for human consumption
- Not intended to diagnose, treat, cure, or prevent any disease
Quality & Manufacturing
- Lot-specific COA
- Lyophilized for transit stability; batch traceable
- Tamper-evident seal; lot & test date on each vial
- No MOQ for online orders
- Bulk orders for physical locations start at 25-unit minimum
