FOXO4 (10mg)

$320.00

SKU: YPB.255 Categories: , ,

Description

Description

FOXO4-DRI is a senolytic peptide designed to eliminate senescent “zombie” cells by interrupting the FOXO4-p53 interaction, triggering apoptosis in damaged cells without harming healthy ones. It shows promise in reversing age-related physical decline, improving healthspan, reducing inflammation, increasing energy, and reversing chemotherapy-induced damage

  • Targeted Elimination of Senescent Cells: It selectively induces apoptosis in senescent (non-functional, inflammatory) cells by inhibiting their ability to evade death via p53.
  • Enhanced Physical Function and Healthspan: Research indicates it can improve physical fitness, reduce age-related stiffness, and boost overall vitality.
  • Reduced Chronic Inflammation: By clearing senescent cells, it reduces the “zombie cell” load, which decreases inflammatory markers (\(Il-1\beta, Il-6, Tnf-\alpha\)) that contribute to aging.
  • Improved Cardiovascular and Tissue Health: Studies show it can increase vascular elasticity, reduce vascular ROS (reactive oxygen species), and potentially improve liver function.
  • Reversal of Chemotherapy Side Effects: Research suggests it can counteract the negative effects of senescence caused by chemotherapy, such as, for example, doxorubicin-induced damage.
  • Potential Skin Rejuvenation:

Composition

  • FOXO4: 10 mg
  • Appearance: lyophilized powder in a sealed research vial

Research Focus (non-clinical)

  • Investigation of FOXO4-p53 interaction in cellular senescence models
  • Studies of apoptosis induction pathways in aging research
  • Peptide identity and purity verification via HPLC/LC-MS
  • Stability and solubility profiling under various laboratory storage conditions

Documentation

  • Lot-specific COA available
  • Batch and lot traceability

Important Notice

  • For research use only
  • Not for human consumption
  • Not intended to diagnose, treat, cure, or prevent any disease

Quality & Manufacturing

  • Lot-specific COA
  • Lyophilized for transit stability; batch traceable
  • Tamper-evident seal; lot & test date on each vial
  • No MOQ for online orders
  • Bulk orders for physical locations start at 25-unit minimum

Storage Instructions

All products are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.

Certificate of Analysis

Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.

View Certificate of Analysis

Testing Protocol

Third-Party Lab Verified

Quantitative Assay

Heavy Metals Screened

Sterility Testing (TAMC)

Yeast & Mold Testing (TYMC)

Testing performed per USP compendial standards by independent analytical laboratory

Questions about this product